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货号: STA00302
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: 5T4
应用: WB IP
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 72kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IP 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : 5T4 Antibody detects endogenous levels of total 5T4
别名 : 5T4; 5T4AG; M6P1; TPBG; 5T4 oncofetal antigen;Trophoblast glycoprotein;
数据库链接:
背景:
5T4 is a 72 kDa transmembrane glycoprotein that exhibits restricted expression in human and mouse adult tissues, is upregulated on many carcinomas and tumour expression correlates with poorer clinical outcome in ovarian, gastric and colorectal cancers. mES cells lack cell surface expression of the 5T4 antigen, and both protein and mRNA are rapidly upregulated following induction of differentiation. This proteins expression correlates with downregulation of OCT-4 and Tra-1–60.


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