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alpha smooth muscle Actin Antibody

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说明书下载
货号: STA00002
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: alpha
应用: WB IHC ICC/IF FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 42kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:1000~1:10000 IHC 1:500~1:1000 ICC/IF 1:100~1:500 FC 1:20
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal

抗原&靶点信息

特异性 : alpha smooth muscle Actin Antibody detects endogenous levels of total alpha smooth muscle Actin
别名 : Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS, GIG46

数据库链接:

Organism

基因 ID

SwissProt

背景:

Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.

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