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货号: STA00002
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: alpha
应用: WB IHC ICC/IF FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 42kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:10000 IHC 1:500~1:1000 ICC/IF 1:100~1:500 FC 1:20
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : alpha smooth muscle Actin Antibody detects endogenous levels of total alpha smooth muscle Actin
别名 : Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, ACTA2, ACTSA, ACTVS, GIG46
数据库链接:
背景:
Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.


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