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货号: STA00194
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: ATM
应用: WB IHC ICC/IF FC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 350kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:200 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : ATM Antibody detects endogenous levels of total ATM
别名 : A-T, mutated; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; EC 2.7.11.1; kinase ATM; Serine-protein kinase ATM
数据库链接:
背景:
ATM encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1.


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