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FoxO3a Antibody

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说明书下载
货号: STA00084
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: FoxO3a
应用: WB IHC ICC/IF
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 90kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal

抗原&靶点信息

特异性 : FoxO3a Antibody detects endogenous levels of total FoxO3a
别名 : Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3; FKHRL1; FOXO3A

数据库链接:

Organism

基因 ID

SwissProt

背景:

FoxO3a is a transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

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