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货号: STA00277
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: RAIDD
应用: WB IHC ICC/IF IP FC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 23kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : RAIDD Antibody detects endogenous levels of total RAIDD
别名 : CRADD;MGC9163;RAIDD;Death adaptor molecule RAIDD;Death domain containing protein CRADD;
数据库链接:
背景:
The receptor interacting protein RIP is a death domain-containing serine/threonine kinase which associates with FAS or the TNF-R1 binding protein TRADD. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.


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