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货号: TPFL0343
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: ATG7
应用: WB, IHC, IF/ICC, FC , ELISA
反应性 : human, mouse, rat, pig
宿主物种 : Mouse
MW(CalcμLated) : 78 kDa
MW(Observed): 68-78 kDa
同种型-Isotype : IgG2a
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1500 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : ATG7
蛋白名称 : ATG7 autophagy related 7 homolog (S. cerevisiae)
别名 : 2B5A10, APG7 LIKE, APG7L, ATG12-activating enzyme E1 ATG7, Autophagy related protein 7
背景:
Atg7 is an E1-like enzyme that is specifically involved in autophagosome formation and is essential for autophagy. As an autophagic-related protein it is required for linking to Atg12, Atg5 and Atg8, which are essential for Atg conjugation and autophagosome formation. Atg7 has been reported as an important regulator of autophagy with starvation-induced or chemotherapeutic agent treatment. The high expression level of ATG7 is related to the survival of patients with breast cancer. There are several isoforms of ATG7 protein ranged from 68 kDa to 78 kDa.


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