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C3/C3b/C3c Monoclonal antibody

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说明书下载
货号: TPFL0339
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: C3
应用: WB, IHC, IF/ICC, ELISA
反应性 : human, mouse
宿主物种 : Mouse
MW(CalcμLated) : 1663 aa, 187 kDa
MW(Observed): 115 kDa
同种型-Isotype : IgG1
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein G purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal

抗原&靶点信息

基因名称 : C3
蛋白名称 : complement component 3
别名 : C3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, Complement C3, Complement component C3, CPAMD1

数据库链接:

Organism

基因 ID

SwissProt

背景:

The complement system is an important effector that bridges the innate and adaptive immune systems (PMID: 20010915). The third component of complement, C3, plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways (PMID: 11414361). Human C3, composed of α and β chains (115 and 75 kDa, respectively), is cleaved into C3a and C3b by C3 convertase. C3b is further cleaved into iC3b, C3c, C3dg and C3f. This antibody raised against 1314-1663 aa of human C3 protein recognizes the C3 alpha chain, C3b alpha' chain, and C3c alpha' chain fragment 2.

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