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货号: TPFL0337
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: CD63
应用: WB, IHC, IF-P, ELISA
反应性 : human
宿主物种 : Mouse
MW(CalcμLated) : 26 kDa
MW(Observed): 35 kDa
同种型-Isotype : IgG1
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein G purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : CD63
蛋白名称 : CD63 molecule
别名 : 3D4D1, CD 63, CD63 antigen, Limp1, Lysosomal-associated membrane protein 3
背景:
CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediate signal transduction events that play a role in the regulation of cell development, activation and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.


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