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货号: TPFL0334
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: Fibronectin
应用: WB, IHC, IF/ICC, IF-P, IP, ELISA
反应性 : human, mouse, rat
宿主物种 : Mouse
MW(CalcμLated) : 2386 aa, 263 kDa
MW(Observed): 263 kDa
同种型-Isotype : IgG1
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein G purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : Fibronectin
蛋白名称 : fibronectin 1
别名 : FN1, 1G10F9, Anastellin, CIG, Cold insoluble globulin
背景:
Fibronectin 1 (FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellular matrix (cellular FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. Cellular FN (dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis. (PMID: 7276612; 12244123; 12847088)


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