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货号: TPFL0330
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: HDAC4
应用: WB, IHC, IF/ICC, IF-P, IP, ELISA
反应性 : human, mouse
宿主物种 : Mouse
MW(CalcμLated) : 972 aa, 106 kDa
MW(Observed): 140 kDa
同种型-Isotype : IgG2a
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1500 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : HDAC4
蛋白名称 : histone deacetylase 4
别名 : 1D2G12, EC:3.5.1.98, HD4, KIAA0288
背景:
HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.


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