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货号: TPFL0315
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: PI3 Kinase p85 Alpha
应用: WB, IHC, IP, ELISA
反应性 : human, mouse, rat, pig, rabbit
宿主物种 : Mouse
MW(CalcμLated) : 85 kDa
MW(Observed): 85 kDa
同种型-Isotype : IgG2a
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 2000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : PI3 Kinase p85 Alpha
蛋白名称 : phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
别名 : P85a; PIK3R1, PI3K p85 alpha, PI3K p85 α, PIK3R1, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha
背景:
Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of INS and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.


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