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货号: TPFL0311
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: TLR4
应用: WB, IHC, ELISA
反应性 : human, mouse, rat, pig
宿主物种 : Mouse
MW(CalcμLated) : 839 aa, 96 kDa
MW(Observed): 100-110 kDa
同种型-Isotype : IgG2b
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : TLR4
蛋白名称 : toll-like receptor 4
别名 : 3G9A4, ARMD10, CD284, hToll, TOLL
背景:
TLR4, also named CD284, belongs to the Toll-like receptor family. TLR4 interacts with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kB activation, cytokine secretion, and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.


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