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详细信息
推荐稀释比 : IHC/IF 1:400-1:1000
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : APP
蛋白名称 : Amyloid-beta precursor protein
别名 : ABPP, APP, N-APP, Abeta40, Beta-APP40, App, Aβ40, A beta 40beta Amyloid 40
背景:
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major formsparticularly Aβ40without increasing Aβ42 levels. | |


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