信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

Anti -HMGB1 Rabbit pAb

复制产品信息

说明书下载
货号: TPFL0292
货期: 现货
价格: 1650;950
+

所属分类:


靶点: HMGB1
应用: WB | IHC/IF
反应性 : H,M,R | H,M,R
宿主物种 : Rabbit
MW(CalcμLated) : 25 kDa
MW(Observed): 25 kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:1000; IHC/IF 1:300-1:3000
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : HMGB1
蛋白名称 : High mobility group protein B1
别名 : HMGB1, HMG1, HMG3, SBP-1, HMG-1, high mobility group box 1

数据库链接:

Organism

基因 ID

SwissProt

Mus musculus
背景:

Like the histones, HMGB1 is among the most important chromatin proteins. In the nucleus HMGB1 interacts withnucleosomes, transcription factors, and histones. This nuclear protein organizes the DNA and regulates transcription.After binding, HMGB1 bendsDNA, which facilitates the binding of other proteins. HMGB1 supports transcription of many genes in interactions with many transcription factors. It also interacts with nucleosomes to loosen packed DNA and remodel the chromatin. Contact with core histones changes the structure of nucleosomes. | |

细胞定位 : Cytoplasm, nucleus, cell membrane, secreted, endosome, endoplasmic reticulum-Golgi intermediate compartment

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交