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货号: TPFL0292
货期: 现货
价格: 1650;950
所属分类:
靶点: HMGB1
应用: WB | IHC/IF
反应性 : H,M,R | H,M,R
宿主物种 : Rabbit
MW(CalcμLated) : 25 kDa
MW(Observed): 25 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:1000; IHC/IF 1:300-1:3000
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : HMGB1
蛋白名称 : High mobility group protein B1
别名 : HMGB1, HMG1, HMG3, SBP-1, HMG-1, high mobility group box 1
背景:
Like the histones, HMGB1 is among the most important chromatin proteins. In the nucleus HMGB1 interacts withnucleosomes, transcription factors, and histones. This nuclear protein organizes the DNA and regulates transcription.After binding, HMGB1 bendsDNA, which facilitates the binding of other proteins. HMGB1 supports transcription of many genes in interactions with many transcription factors. It also interacts with nucleosomes to loosen packed DNA and remodel the chromatin. Contact with core histones changes the structure of nucleosomes. | |


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