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货号: TPFL0279
货期: 现货
价格: 1650;950
所属分类:
靶点: N Cadherin
应用: WB | IHC/IF
反应性 : H,M,R | H,M,R,Pig
宿主物种 : Rabbit
MW(CalcμLated) : 100 kDa
MW(Observed): 110-140 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:1000; IHC/IF 1:400-1:1600
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : CDH2
蛋白名称 : Cadherin-2
别名 : Neural cadherin, N-cadherin, CD325, CDw325, Cadherin 2 N cadherin neuronal, CDHN, Cdh2, Cadherin 2 type 1, NCAD, N cadherin 1
背景:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. | |


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