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货号: TPFL0232
货期: 现货
价格: 980;4000;6000
所属分类：
靶点: Beta Actin
应用： WB, IHC, IF/ICC, ELISA
反应性 ： human, mouse, rat, canine, monkey
宿主物种 ： Rabbit
MW(CalcμLated) ： 375 aa, 42 kDa
MW(Observed)： 42 kDa
同种型-Isotype ： IgG
偶联-Conjugate ： Unconjugated
隐藏域元素占位
详细信息
组成 ： PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 ： Antigen affinity purification
储存 ： Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 ： 600 ug/ml
克隆性 ： Polyclonal
抗原&靶点信息
基因名称 ： Beta Actin
蛋白名称 ： actin, beta
别名 ： ACTB, Actin, bate actin, β actin, Actin cytoplasmic 1
背景：
Beta Actin, also named as ACTB and F-Actin, belongs to the actin family. Actins are highly conserved globular proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. At least six isoforms of actins are known in mammals and other vertebrates: alpha (ACTC1, cardiac muscle 1), alpha 1 (ACTA1, skeletal muscle) and 2 (ACTA2, aortic smooth muscle), beta (ACTB), gamma 1 (ACTG1) and 2 (ACTG2, enteric smooth muscle). Beta and gamma 1 are two non-muscle actin proteins. Most actins consist of 376aa, while ACTG2 (rich in muscles) has 375aa and ACTG1(found in non-muscle cells) has only 374aa. Beta actin has been widely used as the internal control in RT-PCR and Western Blotting as a 42-kDa protein. However, the 37-40, 31, 15 kDa cleaved fragment of beta actin can be generated during apoptosis process. This antibody was generated against N-terminal region of human beta actin protein and can cross-react with other actins. (9173887, 11217076, 10229193 )
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