产品服务
信号通路
货号: TPFL0224
货期: 现货
价格: 1150;1870;2900
所属分类:
靶点: Caspase-9
应用: WB, IP, IF/ICC, IHC-P, ELISA
反应性 : Human, Mouse, Rat
宿主物种 : Rabbit
MW(CalcμLated) : 46 kDa
MW(Observed): 46 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:300 - 1:5000 IP 0.5 μg - 4 μg antibody for 400 μg - 600 μg extracts of whole cells IF/ICC 1:50 - 1:100 IHC-P 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
组成 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS, pH 7.3, containing 50% glycerol. Preserved with Proclin300 or sodium azide. May contain 0.05% BSA as specified on the Certificate of Analysis.
纯化工艺 : Affinity purification
储存 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : CASP9
蛋白名称 : Caspase-9
别名 : MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9
背景:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.


微信客服