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货号: TPFL0216
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: CD86
应用: WB, IF-P, ELISA
反应性 : human
宿主物种 : Rabbit
MW(CalcμLated) : 329 aa, 38 kDa
MW(Observed): 65 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 700 ug/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : CD86
蛋白名称 : CD86 molecule
别名 : CD86, Activation B7 2 antigen, Activation B7-2 antigen, B7 2, B70
背景:
CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.


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