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货号: TPFL0211
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: Claudin 1
应用: WB, IHC, IF/ICC, ELISA
反应性 : human, mouse, rat, canine
宿主物种 : Rabbit
MW(CalcμLated) : 211 aa, 23 kDa
MW(Observed): 20-23 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 600 ug/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : Claudin 1
蛋白名称 : claudin 1
别名 : Caudin 1, CLDN1, Claudin-1, CLD1, ILVASC
背景:
Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small (20-27 kilodalton (kDa)) proteins with similar structures. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. Claudin-1 is an integral membrane protein expressed primarily in keratinocytes and normal mammary epithelial cells. Claudin 1 forms tight junctions with other claudin proteins and plays an important role in the intestinal epithelial barrier.


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