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Collagen Type I Polyclonal antibody

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说明书下载
货号: TPFL0208
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: COL1A2
应用: WB, IHC, IF-P, FC , IP, ELISA
反应性 : human, pig
宿主物种 : Rabbit
MW(CalcμLated) : 1366 aa, 130 kDa
MW(Observed): 130-160 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 960 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : COL1A2
蛋白名称 : collagen, type I, alpha 2
别名 : COL1, COL1A2, Alpha-2 type I collagen, col I, Collagen alpha 2(I) chain

数据库链接:

Organism

基因 ID

SwissProt

背景:

Type I collagen, the major structural component of connective tissues such as skin, tendon and bone, is the most abundant and widely expressed collagen in humans (PMID: 7620364; 8645190; 9016532). Type I collagen is a heterotrimer comprising one alpha 2(I) and two alpha 1(I) chains which are encoded by the unlinked loci COL1A2 and COL1A1 respectively. Mutations in COL1A2 gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, idiopathic osteoporosis, and atypical Marfan syndrome. This antibody raised against 1017-1366 aa of human pro-alpha 2 chain of type l collagen can recognize collagen alpha 2(1) chain and C-terminal propeptide of pro-alpha 2(1) chain.

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