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Cytokeratin 19 Polyclonal antibody

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说明书下载
货号: TPFL0203
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: Cytokeratin 19
应用: WB, IHC, IF/ICC, IF-P, FC , ELISA
反应性 : human, mouse
宿主物种 : Rabbit
MW(CalcμLated) : 40 kDa
MW(Observed): 44-50 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 600 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : Cytokeratin 19
蛋白名称 : keratin 19
别名 : CK 19, CK19, KRT19, CK-19, Cytokeratin,Keratin

数据库链接:

Organism

基因 ID

SwissProt

背景:

Cytokeratin 19 (CK19 or KRT19) is a type I (acidic) cytokeratin. It is an intermediate filament protein providing structural rigidity and multipurpose scaffolds in epithelial cells. CK19 is often overexpressed in various cancers (e.g., hepatocellular carcinoma [HCC], pancreatic adenocarcinoma, lung cancer) and serves as a biomarker for hepatic progenitor cells (HPCs) associated with poor prognosis in HCC patients . Additionally, CK19 expression is common in pancreatic and gastrointestinal adenocarcinomasand has been studied as a potential diagnostic and prognostic marker for pancreatic neuroendocrine tumors (PNETs), where positive CK19 expression correlates with poor prognosis. Serum CK19 fragments (e.g., CYFRA 21-1, CK19-2G2) have been investigated as tumor markers for lung and breast cancer, with preoperative levels associated with metastasis and survival.

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