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货号: TPFL0183
货期: 现货
价格: 1685.96
所属分类：
靶点: Histone H3
应用： WB, PepArr, IP
反应性 ： Mouse, Rat, Human
宿主物种 ： Rabbit
MW(CalcμLated) ： 15 kDa
MW(Observed)： 17 kDa
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： IP: 1/1000；WB: 1 µg/mL
组成 ： pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
纯化工艺 ： Affinity purification Immunogen
储存 ： Form: Liquid，Shipping condition: Blue Ice，Short-term storage (1–2 weeks): +4°C，Long-term storage: -20°C，Aliquot information:，Aliquot upon delivery，Storage note: Avoid freeze-thaw cycles.
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： <p>ab5103 detects a 17 kDa band in single lane Western Blot. Peptide inhibition in Western Blot hasn't been processed. Modification specificity is determined by Peptide Array. ab5103 binds strongly to Histone H3 citrulline 2 &#43; 8 &#43; 17 peptide.</p><p>In our hands, when tested in western blot, this product typically gives a weaker signal in mouse and rat tissue lysates compared to mouse and rat cell lines.</p><p>From Mar 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help. &nbsp;You may also be interested in our alternative recombinant antibody, ab281584&#46;</p>
基因名称 ： H3C1
蛋白名称 ： Histone H3.1
别名 ： H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, H3C1, H3FC, HIST1H3C, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3R2cit
背景：
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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