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货号: TPFL0141
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: Progesterone Receptor
应用: WB, IHC, IF/ICC, IF-P, ELISA
反应性 : human, mouse
宿主物种 : Rabbit
MW(CalcμLated) : 933 aa, 99 kDa
MW(Observed): 80 kDa, 110-115 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 900 ug/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : Progesterone Receptor
蛋白名称 : progesterone receptor
别名 : PGR, NR3C3, PR, PRGR
背景:
PGR (Progesterone Receptor), also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence. This antibody recognizes both PR-A and PR-B.


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