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货号: TPFL0133
货期: 现货
价格: 1180.00;1980.00;2800.00
所属分类:
靶点: HIF-1 Alpha
应用: Flow-Cyt, ICC/IF
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 92 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : Flow-Cyt 1μg/Test; ICC/IF 1:100-500
组成 : 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
纯化工艺 : affinity purified by Protein A
储存 : Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
浓度 : 1mg/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : HIF1A
蛋白名称 : Hypoxia-inducible factor 1-alpha
别名 : HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78; HIF1alpha; HIF1A_HUMAN; HIF1A; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78 (bHLHe78); Member of PAS protein 1; PAS domain-containing protein 8; HIF1A_MOUSE; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); Class E basic helix-loop-helix protein 78
背景:
Hypoxia-inducible factor 1 alpha is not only particularly important for the body to maintain normal physiological functions under hypoxic conditions, but also plays an important role in pathological processes such as tumor growth and neuronal apoptosis. HIF1 alpha can regulate the expression levels of many downstream genes. Mammalian cells exhibit HIF under hypoxic stress conditions. HIF is a transcription factor that stabilizes cells in response to hypoxia.


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