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WNT7A/B Polyclonal antibody

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说明书下载
货号: TPFL0102
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: WNT7A
应用: WB, IHC, IF/ICC, IP, ELISA
反应性 : human, mouse
宿主物种 : Rabbit
MW(CalcμLated) : 39 kDa
MW(Observed): 30-39 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 750 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : WNT7A
蛋白名称 : wingless-type MMTV integration site family, member 7A
别名 : WNT7B, WNT7A, Protein Wnt 7a, Protein Wnt-7a

数据库链接:

Organism

基因 ID

SwissProt

背景:

The Wnt gene family encodes secreted signaling molecules that bind to frizzled receptors and influence oncogenesis and developmental processes, including regulation of cell fate and patterning during embryogenesis. Wnt7a is normally expressed in several organs, including the lung, testis, lymph node, and brain. As an oncogenic autocrine glycoprotein, Wnt7a promotes tumor invasion and distant metastasis with cancer-associated fibroblasts. Wnt7b is required for endothelial cells derived from pluripotent stem cells to acquire blood-brain barrier properties and may play an important role in the development of myopia in humans. This antibody can both recognize WNT7A and WNT7B.

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