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Anti-AMPK Alpha 1/PRKAA1 Antibody (Clone#CDD-16)

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货号: TPFL0097
货期: 现货
价格: 1280;2180;2800
+

所属分类:


靶点: PRKAA1
应用: WB, IHC-P, IF/ICC, IP, FCM
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 64 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

推荐稀释比 : Western blot (WB): 1:500-2000; Immunohistochemistry (IHC): 1:50-200; Immunocytochemistry/Immunofluorescence (ICC/IF): 1:50-200; ImmunoPrecipitation (IP): 1:20; Flow Cytometry (FCM): 1:20
组成 : 500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化工艺 : Affinity-chromatography
储存 : 12 months from date of receipt,-20℃ as supplied.
浓度 : 500 ug/ml
克隆性 : Monoclonal

抗原&靶点信息

基因名称 : PRKAA1
别名 : AMPK; AMPK alpha; AMPK alpha 1; AMPK subunit alpha 1; AMPK1; AMPKa1; PRKAA1

数据库链接:

Organism

基因 ID

SwissProt

背景:

5'-AMP-activated protein kinase catalytic subunit alpha-1 is an enzyme that in humans is encoded by the PRKAA1 gene. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways.

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