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货号: TPFL0083
货期: 现货
价格: 980;1600
所属分类：
靶点: Cardiac Troponin T
应用： WB, IHC-P, IF-Tissue
反应性 ： Human, Mouse, Rat
宿主物种 ： Rabbit
MW(CalcμLated) ： Predicted band size: 36 kDa
MW(Observed)： 43 kDa
同种型-Isotype ： IgG
偶联-Conjugate ： unconjugated
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:2,000-1:10,000 IHC-P 1:2,000 IF-Tissue 1:500
组成 ： 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
来源 ： Rabbit
纯化工艺 ： Protein A affinity purified.
储存 ： Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.
克隆性 ： Monoclonal
克隆号 ： SC64-03
抗原&靶点信息
蛋白名称 ： Cardiac Troponin T
别名 ： Cardiac muscle troponin T antibody; Cardiomyopathy dilated 1D (autosomal dominant) antibody; Cardiomyopathy hypertrophic 2 antibody; CMD1D antibody; CMH2 antibody; CMPD2 antibody; cTnT antibody; LVNC6 antibody; MGC3889 antibody; OTTHUMP00000033864 antibody; 展开; Cardiac muscle troponin T antibody; Cardiomyopathy dilated 1D (autosomal dominant) antibody; Cardiomyopathy hypertrophic 2 antibody; CMD1D antibody; CMH2 antibody; CMPD2 antibody; cTnT antibody; LVNC6 antibody; MGC3889 antibody; OTTHUMP00000033864 antibody; OTTHUMP00000033865 antibody; OTTHUMP00000033866 antibody; OTTHUMP00000033867 antibody; OTTHUMP00000033870 antibody; OTTHUMP00000218095 antibody; RCM3 antibody; TNNT 2 antibody; TNNT2 antibody; TNNT2_HUMAN antibody; TnTc antibody; Troponin T cardiac muscle antibody; Troponin T type 2 (cardiac) antibody; Troponin T type 2 cardiac antibody; Troponin T, cardiac muscle antibody; Troponin T2 cardiac antibody; 折叠
背景：
Actin is a highly conserved protein that is expressed in all eukaryotic cells. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. Myosin is a hexamer of two heavy chains (MHC) and four light chains (MLC) that interacts with Actin to generate the force for diverse cellular movements, including cytokinesis, phagocytosis and muscle contraction. Troponin facilitates the interaction between Actin and Myosin by binding to calcium. Troponin is made up of at least two subunits, which are divergent in cardiac muscle, fast skeletal muscle and slow skeletal muscle. Structures of skeletal muscle troponin are composed of Troponin C (the sensor), Troponin I (the regulator) and Troponin T (the link to the muscle thin filament). Troponin C is dumbbell-shaped and has a hydrophobic pocket that increases the contractile force of muscle fibers. Troponin C has two isoforms: fast and slow. Fast Troponin C has two calcium binding sites, while slow/cardiac Troponin C has a single calcium binding site.
细胞定位 ： Cytoplasm, filament.
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