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货号: TPFL0079
货期: 现货
价格: 790;1240;1990;3790
所属分类:
靶点: T-cell surface glycoprotein CD4
应用: WB, IHC, IF, FCM
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 51 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:5000
组成 : PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
储存 : -20°C (avoid freeze-thaw cycles), 2 years
克隆性 : Monoclonal
克隆号 : L14G17
抗原&靶点信息
特异性 : CD4 Antibody (Rabbit mAb) [L14G17]
基因名称 : CD4
蛋白名称 : T-cell surface glycoprotein CD4
别名 : CD4 | T-cell surface glycoprotein CD4 | T-cell surface antigen T4/Leu-3
背景:
CD4 is a 55-60 kDa monomeric glycoprotein that is a member of the immunoglobulin supergene family and serves as a co-receptor in MHC class II-restricted T cell activation. It is expressed on approximately 60% of peripheral blood T lymphocytes. It is essential for immune function, facilitating adhesion by binding to MHC class II antigens on antigen-presenting cells (APCs) and enhancing TCR/CD3 signaling during T cell activation. CD4 also plays a critical role in thymocyte differentiation and T lymphocyte/B lymphocyte adhesion and serves as the primary receptor for HIV retroviruses.


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