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货号: TPFL0072
货期: 现货
价格: 1200;2200;3750
所属分类:
靶点: CYP27A1
应用: WB, ELISA
反应性 : Mouse, Rat
宿主物种 : Rabbit
MW(CalcμLated) : 60kDa
MW(Observed): 55kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:2000 - 1:10000 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
组成 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
纯化工艺 : Affinity purification
储存 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA
克隆性 : Monoclonal
克隆号 : ARC59606
抗原&靶点信息
基因名称 : CYP27A1
蛋白名称 : Sterol 26-hydroxylase, mitochondrial
别名 : CTX; CP27; CYP27; CYP27A1
背景:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.


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