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货号: TPFL0061
货期: 现货
价格: 790;1240;1990;3790
所属分类:
靶点: NeuN
应用: WB, IHC, IF, FCM
反应性 : Human, Mouse, Rat, Dog, Zebrafish, Sheep, Goat, Cat, Common marmoset, Cynomolgus monkey, Pig
宿主物种 : Rabbit
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000-1:10000
组成 : PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
储存 : –20°C (avoid freeze-thaw cycles), 2 years
克隆性 : Monoclonal
克隆号 : J1P15
抗原&靶点信息
特异性 : NeuN Antibody (Rabbit mAb) [J1P15]
基因名称 : RBFOX3
蛋白名称 : RNA binding protein fox-1 homolog 3
别名 : FLJ56884 | FLJ58356 | fox-1 homolog C | Fox-3 | FOX3 | hCG_1776007 | hexaribonucleotide binding protein 3 | HRNBP3 | NEUN | NeuN antigen | neuronal nuclei | Neuronal nuclei antigen | RBFOX3 | RFOX3 | RNA binding fox-1 homolog 3 | RNA binding protein fox-1 homolog 3 | RNA binding protein | fox-1 homolog 3
背景:
NEUN, also known as Fox-3, RBFOX3 (RNA binding protein, fox-1), or Fox-1 homolog C, is a 350-amino acid protein containing an RRM (RNA recognition motif) domain. NEUN (Fox-3) localizes to the nucleus and cytoplasm and contains an RNA recognition motif that acts as a splicing regulator and modulates alternative splicing events. It is a nuclear protein expressed in most postmitotic neurons of the central and peripheral nervous systems. It regulates alternative splicing of NumB, promoting neuronal differentiation during development.


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