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货号: TPFL0050
货期: 现货
价格: 790;1240;1990;3790
所属分类：
靶点: MAPK 14
应用： WB, IP, IHC, IF, FCM
反应性 ： Human, Mouse, Rat, Monkey, Mink, Pig, S. cerevisiae, Hamster, Chicken, Zebrafish, Bovine
宿主物种 ： Rabbit
MW(CalcμLated) ： 43 kDa
同种型-Isotype ： IgG
偶联-Conjugate ： Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:1000
组成 ： PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
储存 ： –20°C (avoid freeze-thaw cycles), 2 years
克隆性 ： Monoclonal
克隆号 ： M21L8
抗原&靶点信息
特异性 ： Phospho-p38 MAPK (Thr180/Tyr182) Antibody (Rabbit mAb) [M21L8] 仅在 Thr180 和 Tyr182 处磷酸化时才检测内源性 p38 MAPK 水平。该抗体不会与 p42/44 MAPK 或 SAPK/JNK 的磷酸化形式发生交叉反应。
别名 ： CSAID-binding protein | Csaids binding protein | CSBP | CSBP1 | CSBP2 | CSPB1 | cytokine suppressive anti-inflammatory drug binding protein | Cytokine suppressive anti-inflammatory drug-binding protein | ERK-6 | ERK3 | ERK6 | EXIP | Extracellular signal-regulated kinase 6 | MAP kinase 11 | MAP kinase 12 | MAP kinase 13 | MAP kinase 14 | MAP kinase MXI2 | MAP kinase p38 alpha | MAP kinase p38 beta | MAP kinase p38 delta | MAP kinase p38 gamma | MAPK 11 | MAPK 12 | MAPK 13 | MAPK 14 | MAPK-13 | MAPK11 | MAPK12 | MAPK13 | MAPK14 | MAX-interacting protein 2 | MGC99536 | Mitogen-activated protein kinase 11 | Mitogen-activated protein kinase 12 | Mitogen-activated protein kinase 13 | Mitogen-activated protein kinase 14 | mitogen-activated protein kinase 3 | Mitogen-activated protein kinase p38 alpha | Mitogen-activated protein kinase p38 beta | Mitogen-activated protein kinase p38 delta | Mitogen-activated protein kinase p38 gamma | mitogen-activated protein kinase p38-2 | MK11 | MK12 | MK13 | MK14 | MXI2 | p38 | p38 MAP kinase | p38 mitogen activated protein kinase | p38-2 | p38-alpha | P38A | p38ALPHA | p38alpha Exip | p38b | p38Beta | P38BETA2 | P38D | p38delta | P38G | P38GAMMA | PRKM11 | PRKM12 | PRKM13 | PRKM14 | PRKM15 | RK | SAPK-3 | SAPK2 | SAPK2A | SAPK2B | SAPK3 | SAPK4 | Stress-activated protein kinase 2 | stress-activated protein kinase 2A | Stress-activated protein kinase 2b | Stress-activated protein kinase 3 | Stress-activated protein kinase 4 | stress-activated protein kinase-2 | stress-activated protein kinase-2b
背景：
p38 MAP kinase (MAPK), also known as RK or CSBP, is the yeast HOG kinase in mammals, involved in cellular responses to cytokines and stress. It is activated by MKK3, MKK6, and SEK through phosphorylation at Thr180 and Tyr182. Activated p38 MAPK phosphorylates and activates MAPK-activated protein kinase 2 (MAPKAP kinase-2), which was initially discovered in skeletal muscle and is also activated by p42/p44 MAPK isoforms.
细胞定位 ： Cytoplasm, cytosol, nucleus, mitochondrion
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