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货号: TPFL0049
货期: 现货
价格: 1400;2500;4250
所属分类:
靶点: Phospho-PERK-T982
应用: WB, IHC-P, ELISA
反应性 : Human, Mouse, Rat
宿主物种 : Rabbit
MW(CalcμLated) : 125kDa
MW(Observed): 170kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500 - 1:1000 IHC-P 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
组成 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
纯化工艺 : Affinity purification
储存 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA
克隆性 : Monoclonal
克隆号 : ARC58934
抗原&靶点信息
基因名称 : EIF2AK3
蛋白名称 : Eukaryotic translation initiation factor 2-alpha kinase 3
别名 : PEK; WRS; PERK; Phospho-PERK-T982
背景:
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.


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