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货号: TPFL0046
货期: 现货
价格: 1650;950
所属分类:
靶点: CD86
应用: WB | IHC/IF
反应性 : M | M
宿主物种 : Rabbit
MW(CalcμLated) : 37 kDa
MW(Observed): 65-85 kDa
同种型-Isotype : IgG, κ
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:1000; IHC/IF 1:500-1:1500
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Monoclonal
克隆号 : SB350
抗原&靶点信息
基因名称 : CD86
蛋白名称 : T-lymphocyte activation antigen CD86
别名 : Activation B7 2 antigen, B7 2, B70, CD28LG2, CD86, CD86 (C-terminal), CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72
背景:
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4.May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation.Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced.Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.; [Isoform 2]: Interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.(Microbial infection) Acts as a receptor for adenovirus subgroup B. | |


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