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Tyrosine Hydroxylase Antibody (Rabbit mAb) [F11M19]

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说明书下载
货号: TPFL0038
货期: 现货
价格: 790;1240;1990;3790
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所属分类:


靶点: TH
应用: WB, IHC, IF
反应性 : Human, Mouse, Rat, Pig
宿主物种 : Rabbit
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:5000
组成 : PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
储存 : –20°C (avoid freeze-thaw cycles), 2 years
克隆性 : Monoclonal
克隆号 : F11M19

抗原&靶点信息

特异性 : Tyrosine Hydroxylase Antibody (Rabbit mAb) [F11M19]
基因名称 : TH
蛋白名称 : Tyrosine 3-monooxygenase
别名 : TYH | TH | Tyrosine 3-monooxygenase | Tyrosine 3-hydroxylase

数据库链接:

Organism

基因 ID

SwissProt

背景:

Tyrosine hydroxylase (TyrH) is a key enzyme in catecholamine synthesis, initiating the conversion of tyrosine to L-DOPA. This enzymatic process is the rate-limiting step in the biosynthetic pathway of catecholamines such as dopamine, adrenaline, and noradrenaline, which act as important hormones and neurotransmitters in the central and peripheral nervous systems. TyrH activation leads to increased production of L-DOPA, which is subsequently decarboxylated to dopamine and transported into synaptic vesicles via vesicular monoamine transporter (VMAT).

细胞定位 : Cytoplasm, perinuclear region

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