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货号: STA02423
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: WRN
应用: WB
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 200kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : WRN Antibody detects endogenous levels of total WRN
别名 : Exonuclease WRN; RecQ3; RECQL2; RECQL3; Werner syndrome helicase; WRN;
数据库链接:
背景:
Multifunctional enzyme that has both magnesium and ATP-dependent DNA-helicase activity and 3'->5' exonuclease activity towards double-stranded DNA with a 5'-overhang. Has no nuclease activity towards single-stranded DNA or blunt-ended double-stranded DNA. Binds preferentially to DNA substrates containing alternate secondary structures, such as replication forks and Holliday junctions.


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