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货号: STA01523
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: TRIM25
应用: WB IHC ICC/IF IP FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 71kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:5000 IHC 1:50~1:200 ICC/IF 1:100~1:500 IP 1:50 FC 1:60
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : TRIM25 Antibody detects endogenous levels of total TRIM25
别名 : EFP; RNF147; TRI25; TRIM 25; Trim25; Z147; ZNF147;
数据库链接:
背景:
Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.


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