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ULK1 Antibody

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说明书下载
货号: STA01271
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: ULK1
应用: WB IHC ICC/IF
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 120kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal

抗原&靶点信息

特异性 : ULK1 Antibody detects endogenous levels of total ULK1
别名 : Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; Unc-51-like kinase 1; ULK1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

Act as a convergence point for multiple signals that control autophagy, and can bind to several autophagy-related (Atg) proteins, regulating phosphorylation states and protein trafficking. AMPK, activated during low nutrient conditions, directly phosphorylates ULK1 at multiple sites including Ser317, Ser555, and Ser777. Conversely, mTOR, which is a regulator of cell growth and an inhibitor of autophagy, phosphorylates ULK1 at Ser757 and disrupts the interaction between ULK1 and AMPK.

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