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货号: STA00852
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: HDAC4
应用: WB ICC/IF
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 140kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:2000 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : HDAC4 Antibody detects endogenous levels of HDAC4
别名 : Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR;
数据库链接:
背景:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.


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