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货号: STA00393
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Myosin
应用: WB IHC ICC/IF FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 200kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Myosin light chain kinase Antibody detects endogenous levels of total Myosin light chain kinase
别名 : KMLS; KRP; MLCK; MYLK; myosin light chain kinase, smooth muscle and non-muscle isozymes; myosin light polypeptide kinase; telokin;
数据库链接:
背景:
Regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance.


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