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货号: STA00250
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SOX2
应用: WB IHC ICC/IF
反应性 : Human Mouse
宿主物种 : Rabbit
MW(Observed): 34kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : SOX2 Antibody detects endogenous levels of total SOX2
别名 : SOX2; ANOP3; MCOPS3; MGC2413; lcc; SRY related HMG box 2;
数据库链接:
背景:
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).


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