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货号: STA00223
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Integrin
应用: WB IHC ICC/IF
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 110kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Integrin beta 3 Antibody detects endogenous levels of total Integrin beta 3
别名 : CD61; GP3A; GPIIIa; Integrin beta-3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITB3; ITGB3;
数据库链接:
背景:
Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity).


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