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货号: STA00135
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: TERT
应用: WB IHC FC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 127 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB: 1:500~1:1000 IHC: 1:50~1:100
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : TERT Antibody detects endogenous levels of total TERT
别名 : TCS1; HEST2; EST2;TRT; Telomerase reverse transcriptase; Telomerase-associated protein 2; Telomerase catalytic subunit;
数据库链接:
背景:
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.


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