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货号: PP0120
货期: 一周
价格: 1900/10mL 15000/100mL
所属分类:
靶点: Nucleophosmin
应用: IHC
反应性 : Human,Mouse,Rat
宿主物种 : Mouse
同种型-Isotype : IgG2a,Kappa
隐藏域元素占位
详细信息
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : 2°C to 8°C/1 year
克隆性 : Monoclonal
抗原&靶点信息
特异性 : The antibody can specifically recognize human Nucleophosmin protein.
基因名称 : NPM1 NPM
蛋白名称 : Nucleophosmin
别名 : NPM1;NPM;Nucleophosmin;NPM;Nucleolar phosphoprotein B23;Nucleolar protein NO38;Numatrin
背景:
This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009],


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