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PD-1 (ABT-PD1) mouse mAb

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说明书下载
货号: PH0247
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: PD1
应用: IHC,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 32kD
MW(Observed): 56kD
同种型-Isotype : IgG1,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-PD1

抗原&靶点信息

特异性 : The antibody can specifically recognize human PD-1 protein.
基因名称 : PDCD1 PD1
蛋白名称 : Programmed cell death protein 1 (Protein PD-1) (hPD-1) (CD antigen CD279)

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],

细胞定位 : Membranous, Cytoplasmic

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