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Insulin (ABT-INS) mouse mAb

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说明书下载
货号: PH0286
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: Insulin
应用: IHC,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 12kD
MW(Observed): 9kD
同种型-Isotype : IgG2b,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-INS

抗原&靶点信息

特异性 : The antibody can specifically recognize human Insulin protein.
基因名称 : INS
蛋白名称 : Insulin [Cleaved into: Insulin B chain; Insulin A chain]

数据库链接:

Organism

基因 ID

SwissProt

背景:

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

细胞定位 : Cytoplasmic

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