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详细信息
推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-MSA
抗原&靶点信息
特异性 : The antibody can specifically recognize proteins from smooth muscle, myocardium and skeletal muscle α actin and smooth muscle derived γ actin, and β actin or non smooth muscle derived γ actin does not respond.
基因名称 : Actin, Muscle Specific
蛋白名称 : α-Skeletal Muscle Actin (α-SA);α-Cardiac Muscle Actin (α-CA);α-Smooth Muscle Actin (α-SMA);γ-Smooth Muscle Actin (γ-SMA);
数据库链接:
背景:
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008],


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