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CD163 (ABT-CD163) mouse mAb

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说明书下载
货号: PH0276
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CD163
应用: IHC,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 125kD
MW(Observed): 125kD
同种型-Isotype : IgG1,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-CD163

抗原&靶点信息

特异性 : The antibody can specifically recognize human CD163 protein.
基因名称 : CD163 M130
蛋白名称 : Scavenger receptor cysteine-rich type 1 protein M130 (Hemoglobin scavenger receptor) (CD antigen CD163)

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011],

细胞定位 : Membranous, Cytoplasmic

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