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Topo IIIα Polyclonal Antibody

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货号: PD2382
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Topo IIIα
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 115kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
基因名称 : TOP3A
蛋白名称 : DNA topoisomerase 3-alpha
别名 : TOP3A;TOP3;DNA topoisomerase 3-alpha;DNA topoisomerase III alpha

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

细胞定位 : Mitochondrion matrix .

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