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XRCC4 Monoclonal Antibody(5C10)

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说明书下载
货号: PH0860
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: XRCC4
应用: WB,IHC,IF,IP
反应性 : Human
宿主物种 : Mouse
MW(Observed): 38kD

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:2000;IP 1:200;IF 1:200;IHC 1:50-300
组成 : PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
纯化工艺 : The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : 5C10

抗原&靶点信息

特异性 : The antibody detects endogenous XRCC4 proteins.
基因名称 : XRCC4
蛋白名称 : DNA repair protein XRCC4
别名 : XRCC4;DNA repair protein XRCC4;X-ray repair cross-complementing protein 4

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],

细胞定位 : Nucleus . Chromosome . Localizes to site of double-strand breaks. .; [Protein XRCC4, C-terminus]: Cytoplasm . Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3). .

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