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货号: PD2866
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: UBE2A/B
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 17kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : UBE2A/B Polyclonal Antibody detects endogenous levels of UBE2A/B protein.
基因名称 : UBE2A/UBE2B
蛋白名称 : Ubiquitin-conjugating enzyme E2 A/Ubiquitin-conjugating enzyme E2 B
别名 : UBE2A;RAD6A;Ubiquitin-conjugating enzyme E2 A;RAD6 homolog A;HR6A;hHR6A;Ubiquitin carrier protein A;Ubiquitin-protein ligase A;UBE2B;RAD6B;Ubiquitin-conjugating enzyme E2 B;RAD6 homolog B;HR6B;hHR6B;Ubiquitin carrier protein B;Ubiquitin-conjugating enzyme E2-17 kDa;Ubiquitin-protein ligase B
数据库链接:
背景:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],


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